Background: The efficacy and safety of the anti-programmed death ligand 1 PD-L1 monoclonal antibody atezolizumab, as compared with those of platinum-based chemotherapy, as first-line treatment for patients with metastatic non-small-cell lung cancer NSCLC with PD-L1 expression are not known. Patients were assigned in a ratio to receive atezolizumab or chemotherapy. Overall survival primary end point was tested hierarchically according to PD-L1 expression status among patients in the intention-to-treat population whose tumors were wild-type with respect to EGFR mutations or ALK translocations. Within the population with EGFR and ALK wild-type tumors, overall survival and progression-free survival were also prospectively assessed in subgroups defined according to findings on two PD-L1 assays as well as by blood-based tumor mutational burden. Results: Overall, patients were enrolled.
What are the next two letters in the series A, E, F, H, I, K, L, M, --, -- .? | Yahoo Answers
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What are the next two letters in the series.... A, E, F, H, I, K, L, M, --, -- .?
In mathematics , Vieta's formulas are formulas that relate the coefficients of a polynomial to sums and products of its roots. Vieta's formulas relate polynomial's coefficients to signed sums of products of the roots r 1 , r 2 , The left-hand sides of Vieta's formulas are the elementary symmetric functions of the roots. Vieta's formulas are frequently used with polynomials with coefficients in any integral domain R. Typically, R is the ring of the integers , the field of fractions is the field of the rational numbers and the algebraically closed field is the field of the complex numbers.
Standing Splits. East Record against Eastern Division opponents. Win Percentage. Games behind.